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PERM Hypothesis: The Fundamental Machinery Able to Elucidate the Role of Xenobiotics and Hormesis in Cell Survival and Homeostasis

In this article the Proteasome, Endoplasmic Reticulum and Mitochondria (PERM) hypothesis is discussed. The complex machinery made by three homeostatic mechanisms involving the proteasome (P), endoplasmic reticulum (ER) and mitochondria (M) is addressed in order to elucidate the beneficial role of ma...

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Detalhes bibliográficos
Main Authors: Salvatore Chirumbolo, Geir Bjørklund
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-01-01
Colecção:International Journal of Molecular Sciences
Assuntos:
Acesso em linha:http://www.mdpi.com/1422-0067/18/1/165
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