Genetic Background of Polycythemia Vera

Polycythemia vera belongs to myeloproliferative neoplasms, essentially by affecting the erythroblastic lineage. JAK2 alterations have emerged as major driver mutations triggering PV-phenotype with the <i>V617F</i> mutation detected in nearly 98% of cases. That’s why JAK2 targeting therap...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Mathilde Regimbeau, Romain Mary, François Hermetet, François Girodon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-04-01
Serier:Genes
Fag:
polycythemia vera
<i>JAK2</i> mutation
erythrocytosis
myeloproliferative neoplasm
mutational landscape
Online adgang:https://www.mdpi.com/2073-4425/13/4/637
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker