The Role of Neutrophils and Neutrophil Elastase in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a severe vasculopathy characterized by the presence of fibrotic lesions in the arterial wall and the loss of small distal pulmonary arteries. The vasculopathy is accompanied by perivascular inflammation and increased protease levels, with neutrophil elastase...

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Bibliografski detalji
Glavni autori: Shalina Taylor, Omar Dirir, Roham T. Zamanian, Marlene Rabinovitch, A. A. Roger Thompson
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018-08-01
Serija:Frontiers in Medicine
Teme:
neutrophils
neutrophil elastase
pulmonary hypertension
pulmonary arterial hypertension
vascular remodeling
Online pristup:https://www.frontiersin.org/article/10.3389/fmed.2018.00217/full
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