Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation

ObjectivesGlucocorticoids, such as dexamethasone (DEX), increase apoptosis in a variety of white cells in nasal polyps and apoptosis is an important factor in the resolution of inflammation. However, the mechanism of glucocorticoids induced apoptosis in nasal polyp remains unclear. In this study the...

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Main Authors: Tae-Hoon Lee, Jung Gwon Nam, Ho Min Lee, Bo-Young Kim, Myung-Koo Kang, Woo Yong Bae, Dae Young Hur, Seong Kook Park
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2014-06-01
Colecção:Clinical and Experimental Otorhinolaryngology
Assuntos:
Apoptosis
Glucocorticoids
Nasal polyps
Organ culture
Ex vivo
MAPKs
Acesso em linha:http://www.e-ceo.org/upload/pdf/ceo-7-112.pdf
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