The Application of Regulatory Cascades in Streptomyces: Yield Enhancement and Metabolite Mining

Streptomyces is taken as an important resource for producing the most abundant antibiotics and other bio-active natural products, which have been widely used in pharmaceutical and agricultural areas. Usually they are biosynthesized through secondary metabolic pathways encoded by cluster situated gen...

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Bibliographic Details
Main Authors: Haiyang Xia, Xiaofang Li, Zhangqun Li, Xinqiao Zhan, Xuming Mao, Yongquan Li
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
antibiotic production
regulatory cascades
rewiring regulatory network
unlocking cryptic metabolites
Streptomyces
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00406/full
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