Comprehensive molecular biomarker identification in breast cancer brain metastases

Abstract Background Breast cancer brain metastases (BCBM) develop in about 20–30% of breast cancer (BC) patients. BCBM are associated with dismal prognosis not at least due to lack of valuable molecular therapeutic targets. The aim of the study was to identify new molecular biomarkers and targets in...

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Hauptverfasser: Hans-Juergen Schulten, Mohammed Bangash, Sajjad Karim, Ashraf Dallol, Deema Hussein, Adnan Merdad, Fatma K. Al-Thoubaity, Jaudah Al-Maghrabi, Awatif Jamal, Fahad Al-Ghamdi, Hani Choudhry, Saleh S. Baeesa, Adeel G. Chaudhary, Mohammed H. Al-Qahtani
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2017-12-01
Schriftenreihe:Journal of Translational Medicine
Schlagworte:
Breast cancer brain metastases
Whole transcript array profiling
Pathway and network analysis
snoRNAs
Copy number variations
Whole exome sequencing
Online Zugang:http://link.springer.com/article/10.1186/s12967-017-1370-x
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