Interplay between Interferon-Mediated Innate Immunity and Porcine Reproductive and Respiratory Syndrome Virus

Innate immunity is the first line of defense against viral infection, and in turn, viruses have evolved to evade host immune surveillance. As a result, viruses may persist in host and develop chronic infections. Type I interferons (IFN-α/β) are among the most potent antiviral cytokines triggered by...

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Detalhes bibliográficos
Main Authors: Mingyuan Han, Chiyong Kim, Dongwan Yoo, Jay G. Calvert, Yan Sun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2012-04-01
Colecção:Viruses
Assuntos:
arterivirus
interferon
PRRS
PRRSV
RIG-I
MDA5
NF-κB
JAK-STAT
non-structural proteins
Nsp
nucleocapsid
Acesso em linha:http://www.mdpi.com/1999-4915/4/4/424/
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