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Integrative analysis of DNA methylation and gene expression data identifies EPAS1 as a key regulator of COPD.
Chronic Obstructive Pulmonary Disease (COPD) is a complex disease. Genetic, epigenetic, and environmental factors are known to contribute to COPD risk and disease progression. Therefore we developed a systematic approach to identify key regulators of COPD that integrates genome-wide DNA methylation,...
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| Principais autores: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2015-01-01
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| coleção: | PLoS Genetics |
| Acesso em linha: | http://europepmc.org/articles/PMC4287352?pdf=render |
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