Subcortical and Deep Cortical Atrophy in Frontotemporal Dementia due to Granulin Mutations

Background/Aims: Parkinsonism is often associated with symptoms of frontotemporal dementia (FTD), but its pathogenesis has been largely neglected. In genetic inherited FTD-related granulin (GRN) mutations, parkinsonism is an early sign, and it is more common than in sporadic disorders. Our aim was t...

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Hlavní autoři: Enrico Premi, Valentina Garibotto, Stefano Gazzina, Anna Formenti, Silvana Archetti, Roberto Gasparotti, Alessandro Padovani, Barbara Borroni
Médium: Artigo
Jazyk:Inglês
Vydáno: Karger Publishers 2014-04-01
Edice:Dementia and Geriatric Cognitive Disorders Extra
Témata:
Granulin
Magnetic resonance imaging
Subcortical regions
Basal ganglia
Frontotemporal dementia
Probabilistic atlases
Voxel-based morphometry
On-line přístup:http://www.karger.com/Article/FullText/355428
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