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A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development.

The PARP family member poly(ADP-ribose) polymerase 3 (PARP3) is structurally related to the well characterized PARP1 that orchestrates cellular responses to DNA strand breaks and cell death by the synthesis of poly(ADP-ribose). In contrast to PARP1 and PARP2, the functions of PARP3 are undefined. He...

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Detalhes bibliográficos
Main Authors: Michèle Rouleau, Vishal Saxena, Amélie Rodrigue, Eric R Paquet, Abbie Gagnon, Michael J Hendzel, Jean-Yves Masson, Marc Ekker, Guy G Poirier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3022025?pdf=render
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