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3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases
<p>Abstract</p> <p>Background</p> <p>Metastasis is a major cause of morbidity and mortality in breast cancer with tumor cell invasion playing a crucial role in the metastatic process. PDK1 is a key molecule that couples PI3K to cell proliferation and survival signals in...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2006-03-01
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Colecção: | BMC Cancer |
Acesso em linha: | http://www.biomedcentral.com/1471-2407/6/77 |
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