TNFα Rescues Dendritic Cell Development in Hematopoietic Stem and Progenitor Cells Lacking C/EBPα

Dendritic cells (DCs) are crucial effectors of the immune system, which are formed from hematopoietic stem and progenitor cells (HSPCs) by a multistep process regulated by cytokines and distinct transcriptional mechanisms. C/EBPα is an important myeloid transcription factor, but its role in DC forma...

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Hauptverfasser: Subramanian Anirudh, Angelika Rosenberger, Elke Schwarzenberger, Carolin Schaefer, Herbert Strobl, Armin Zebisch, Heinz Sill, Albert Wölfler
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-05-01
Schriftenreihe:Cells
Schlagworte:
dendritic cell development
monocytic dendritic cell progenitors
C/EBPα
TNFα
Online Zugang:https://www.mdpi.com/2073-4409/9/5/1223
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