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Practical issues in imputation-based association mapping.

Imputation-based association methods provide a powerful framework for testing untyped variants for association with phenotypes and for combining results from multiple studies that use different genotyping platforms. Here, we consider several issues that arise when applying these methods in practice,...

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Detalhes bibliográficos
Main Authors: Yongtao Guan, Matthew Stephens
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2008-12-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC2585794?pdf=render
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