Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

Summary: Comprehensive sequencing approaches have allowed for the identification of the most frequent contributors to cancer, known as drivers. They have also revealed a class of mutations in understudied, infrequently altered genes, referred to as “long tail” (LT) drivers. A key challenge has been...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jessica S. Elman, Thomas K. Ni, Kristen E. Mengwasser, Dexter Jin, Ania Wronski, Stephen J. Elledge, Charlotte Kuperwasser
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019-09-01
Cyfres:Cell Reports
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2211124719311088
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