Purinergic stimulation of K+-dependent Na+/Ca2+ exchanger isoform 4 requires dual activation by PKC and CaMKII

K+-dependent Na+/Ca2+-exchanger isoform 4 (NCXK4) is one of the most broadly expressed members of the NCKX (K+-dependent Na+/Ca2+-exchanger) family. Recent data indicate that NCKX4 plays a critical role in controlling normal Ca2+ signal dynamics in olfactory and other neurons. Synaptic Ca2+ dynamics...

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Bibliografiska uppgifter
Huvudupphovsmän: Xu Yang, Jonathan Lytton
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press, Biochemical Society 2013-12-01
Serie:Bioscience Reports
Ämnen:
Ca2+-calmodulin-dependent kinase II (CaMKII)
K+-dependent Na+/Ca2+-exchanger isoform 4 (NCKX4)
P2Y-purinergic receptor
protein kinase C (PKC)
Länkar:http://www.bioscirep.org/bsr/033/e087/bsr033e087.htm
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