Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis

Epithelial-mesenchymal transition (EMT) is essential in asthma airway remodeling. IL-33 from epithelial cells is involved in pulmonary fibrosis. CD146 has been extensively explored in cancer-associated EMT. Whether IL-33 regulates CD146 in the EMT process associated with asthma airway remodeling is...

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Bibliographische Detailangaben
Hauptverfasser: Zhixiao Sun, Ningfei Ji, Qiyun Ma, Ranran Zhu, Zhongqi Chen, Zhengxia Wang, Yan Qian, Chaojie Wu, Fan Hu, Mao Huang, Mingshun Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-07-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
epithelial-mesenchymal transition
IL-33
CD146
asthma
allergy
Online Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2020.01598/full
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