What goes around comes around: Artificial circular RNAs bypass cellular antiviral responses

Natural circular RNAs have been found to sequester microRNAs and suppress their function. We have used this principle as a molecular tool and produced artificial circular RNA sponges in a cell-free system by in vitro transcription and ligation. Formerly, we were able to inhibit hepatitis C virus pro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Janina Breuer, Patrick Barth, Yannic Noe, Lyudmila Shalamova, Alexander Goesmann, Friedemann Weber, Oliver Rossbach
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-06-01
Colecção:Molecular Therapy: Nucleic Acids
Assuntos:
MT: Non-coding RNAs
circular RNA
circular RNA sponges
innate immune response
immunogenicity
RNA therapy
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2162253122000932
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados