Low dose rapamycin exacerbates autoimmune experimental uveitis.

Rapamycin, a potent immune modulator, is used to treat transplant rejection and some autoimmune diseases. Uveitis is a potentially severe inflammatory eye disease, and 2 clinical trials of treating uveitis with rapamycin are under way. Unexpectedly, recent research has demonstrated that low dose rap...

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Main Authors: Zili Zhang, Xiumei Wu, Jie Duan, David Hinrichs, Keith Wegmann, Gary L Zhang, Mark Hall, James T Rosenbaum
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3344911?pdf=render
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