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Longitudinal changes in plasma Caspase-1 and Caspase-3 during the first 2 years of HIV-1 infection in CD4Low and CD4High patient groups.
Over 95% of CD4 cell death occurs by Caspase-1-mediated pyroptosis during HIV infection. Caspase-3-mediated apoptosis accounts for the death in a small proportion of infected CD4 cells. To date, there have been no reports on the dynamics of Caspase-1 and Caspase-3 and their relationship with disease...
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主要な著者: | , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science (PLoS)
2015-01-01
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シリーズ: | PLoS ONE |
オンライン・アクセス: | http://europepmc.org/articles/PMC4373860?pdf=render |
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