Accessory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX

ABSTRACT Carbapenem-resistant Klebsiella pneumoniae (CRKp) is an urgent public health threat. Worldwide dissemination of CRKp has been largely attributed to clonal group (CG) 258. However, recent evidence indicates the global emergence of a CRKp CG307 lineage. Houston, TX, is the first large city in...

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Main Authors: William C. Shropshire, An Q. Dinh, Michelle Earley, Lauren Komarow, Diana Panesso, Kirsten Rydell, Sara I. Gómez-Villegas, Hongyu Miao, Carol Hill, Liang Chen, Robin Patel, Bettina C. Fries, Lilian Abbo, Eric Cober, Sara Revolinski, Courtney L. Luterbach, Henry Chambers, Vance G. Fowler, Robert A. Bonomo, Samuel A. Shelburne, Barry N. Kreiswirth, David van Duin, Blake M. Hanson, Cesar A. Arias
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2022-04-01
Serija:mBio
Teme:
CG258
CG307
carbapenem-resistant Klebsiella pneumoniae
divergent evolution
genomic surveillance
mobile genetic elements
Online dostop:https://journals.asm.org/doi/10.1128/mbio.00497-22
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