Mitochondrial – nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivoResearch in context

We hypothesized that changes in the mitochondrial DNA (mtDNA) would significantly influence whole body metabolism, adiposity and gene expression in response to diet. Because it is not feasible to directly test these predictions in humans we used Mitochondrial-Nuclear eXchange mice, which have recipr...

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Main Authors: Kimberly J. Dunham-Snary, Michael W. Sandel, Melissa J. Sammy, David G. Westbrook, Rui Xiao, Ryan J. McMonigle, William F. Ratcliffe, Arthur Penn, Martin E. Young, Scott W. Ballinger
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2018-10-01
Sraith:EBioMedicine
Rochtain Ar Líne:http://www.sciencedirect.com/science/article/pii/S2352396418303323
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