Mitochondrial – nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivoResearch in context

We hypothesized that changes in the mitochondrial DNA (mtDNA) would significantly influence whole body metabolism, adiposity and gene expression in response to diet. Because it is not feasible to directly test these predictions in humans we used Mitochondrial-Nuclear eXchange mice, which have recipr...

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Bibliografiset tiedot
Päätekijät: Kimberly J. Dunham-Snary, Michael W. Sandel, Melissa J. Sammy, David G. Westbrook, Rui Xiao, Ryan J. McMonigle, William F. Ratcliffe, Arthur Penn, Martin E. Young, Scott W. Ballinger
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2018-10-01
Sarja:EBioMedicine
Linkit:http://www.sciencedirect.com/science/article/pii/S2352396418303323
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