The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease Progression

Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity and mortality. Oxidative stress and release of pro-inflammatory cytokines, such as tumor necrosis factor α (TNFα), are major consequences of hepatic lipid overload, which can contribute to progression of NAFLD to n...

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Bibliographic Details
Main Authors: Giulia Vecchione, Elena Grasselli, Federica Cioffi, Francesca Baldini, Paulo J. Oliveira, Vilma A. Sardão, Katia Cortese, Antonia Lanni, Adriana Voci, Piero Portincasa, Laura Vergani
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Nutrition
Subjects:
non-alcoholic fatty liver disease
non-alcoholic steatohepatitis
FaO hepatoma cells
lipid metabolism
oxidative stress
silybin
Online Access:http://journal.frontiersin.org/article/10.3389/fnut.2017.00042/full
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