A majority of Brazilian patients with rheumatoid arthritis HLA-DRB1 alleles carry both the HLA-DRB1 shared epitope and anti-citrunillated peptide antibodies

The objective of the present study was to evaluate the contribution of the shared epitope (SE), the rheumatoid arthritis (RA) protection model, and the occurrence of anti-cyclic citrullinated peptide (anti-CCP) antibodies in RA patients from a genetically diverse population. One hundred and forty Br...

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Main Authors: P. Louzada-Júnior, M.V.C. Freitas, R.D.R. Oliveira, N.H.S. Deghaide, R.A. Conde, M.B. Bertolo, E.A. Donadi
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Divulgação Científica 2008-06-01
Colecção:Brazilian Journal of Medical and Biological Research
Assuntos:
Susceptibility to rheumatoid arthritis
HLA
Brazilians
Shared epitope
Anti-cyclic citrullinated peptide
Acesso em linha:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600010
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