Proteomic analysis of endogenous nitrotryptophan-containing proteins in rat hippocampus and cerebellum

Nitration of tryptophan residues is a novel post-translational modification. In the present study, we examined whether NO2Trp (nitrotryptophan)-containing proteins are produced in the hippocampus and cerebellum of the adult rat under physiological conditions in vivo. Using Western blot analysis with...

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Autores principales: Munehiro Uda, Hiroaki Kawasaki, Ayako Shigenaga, Takeshi Baba, Fumiyuki Yamakura
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press, Biochemical Society 2012-09-01
Colección:Bioscience Reports
Materias:
cerebellum
hippocampus
6-nitrotryptophan
proteome
tandem MS analysis
tryptophan residue
Acceso en línea:http://www.bioscirep.org/bsr/032/0521/bsr0320521.htm
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