Suppression of Superficial Microglial Activation by Spinal Cord Stimulation Attenuates Neuropathic Pain Following Sciatic Nerve Injury in Rats

We evaluated the mechanisms underlying the spinal cord stimulation (SCS)-induced analgesic effect on neuropathic pain following spared nerve injury (SNI). On day 3 after SNI, SCS was performed for 6 h by using electrodes paraspinally placed on the L4-S1 spinal cord. The effects of SCS and intraperit...

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保存先:
書誌詳細
主要な著者: Masamichi Shinoda, Satoshi Fujita, Shiori Sugawara, Sayaka Asano, Ryo Koyama, Shintaro Fujiwara, Kumi Soma, Takaaki Tamagawa, Tomoyuki Matsui, Daisuke Ikutame, Masatoshi Ando, Ayaka Osada, Yuki Kimura, Kazutaka Kobayashi, Takamitsu Yamamoto, Kuniko Kusama-Eguchi, Masayuki Kobayashi, Yoshinori Hayashi, Koichi Iwata
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2020-03-01
シリーズ:International Journal of Molecular Sciences
主題:
spinal cord stimulation
spared nerve injury
microglial activation
somatosensory cortex
in vivo optical imaging
オンライン･アクセス:https://www.mdpi.com/1422-0067/21/7/2390
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