The Role and Modulation of Spinal Perineuronal Nets in the Healthy and Injured Spinal Cord

Rather than being a stable scaffold, perineuronal nets (PNNs) are a dynamic and specialized extracellular matrix involved in plasticity modulation. They have been extensively studied in the brain and associated with neuroprotection, ionic buffering, and neural maturation. However, their biological f...

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Bibliographic Details
Main Authors: Judith Sánchez-Ventura, Michael A. Lane, Esther Udina
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
perineuronal nets
CSPGs
spinal cord injury
plasticity
stability
ChABC
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.893857/full
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