Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.

Cornelia de Lange syndrome (CdLS), a disorder caused by mutations in cohesion proteins, is characterized by multisystem developmental abnormalities. PDS5, a cohesion protein, is important for proper chromosome segregation in lower organisms and has two homologues in vertebrates (PDS5A and PDS5B). Pd...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bin Zhang, Jufang Chang, Ming Fu, Jie Huang, Rakesh Kashyap, Ezequiel Salavaggione, Sanjay Jain, Shashikant Kulkarni, Matthew A Deardorff, Maria L Giovannucci Uzielli, Dale Dorsett, David C Beebe, Patrick Y Jay, Robert O Heuckeroth, Ian Krantz, Jeffrey Milbrandt
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2009-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC2672303?pdf=render
Tagiau: Ychwanegu Tag
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