SIRT2 Is Critical for Sheep Oocyte Maturation through Regulating Function of Surrounding Granulosa Cells

Oocyte in vitro maturation is crucial for in vitro embryo production technology, which provides oocytes resources for in vitro fertilization and somatic cell nuclear transfer. Previous studies proved that SIRT2, a member of the sirtuin family, plays a role in oocyte meiosis, but its role in sheep oo...

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Bibliographic Details
Main Authors: Xiaohuan Fang, Wei Xia, Sa Li, Yatian Qi, Mingzhi Liu, Yang Yu, Hanxing Li, Mengqi Li, Chenyu Tao, Zhigang Wang, Junjie Li
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
SIRT2
sheep granulosa cells
oocytes in vitro maturation
mitochondria
mitophagy
Online Access:https://www.mdpi.com/1422-0067/23/9/5013
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