Mechanism and Protective Effect of Smilax glabra Roxb on the Treatment of Heart Failure via Network Pharmacology Analysis and Vitro Verification

Smilax glabra Roxb (SGR) has been widely applied alone or in combination with other Chinese herbs in heart failure (HF), but its mechanism and protective effect have not been investigated. We aimed to explore the mechanism and protective effect of SGR on the treatment of HF. Network pharmacology ana...

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Main Authors: Yingxin Long, Zunjiang Li, Chunxia Huang, Zhongyu Lu, Kuncheng Qiu, Meixing He, Zhijian Fang, Banghan Ding, Xiaohong Yuan, Wei Zhu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2022-05-01
Sraith:Frontiers in Pharmacology
Ábhair:
Smilax glabra Roxb
heart failure
mitochondrial dysfunction
network pharmacology analysis
UHPLC-LTQ-Orbitrap-MSn method
Rochtain Ar Líne:https://www.frontiersin.org/articles/10.3389/fphar.2022.868680/full
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