Peroxiredoxin 6 mediates the protective function of curcumin pretreatment in acute lung injury induced by serum from patients undergoing one-lung ventilation in vitro

Abstract Background Curcumin has attracted much attention due to its wide range of therapeutic effects. In this study, we used serum collected from patients undergoing one-lung ventilation (OLV) to establish an in vitro acute lung injury (ALI) model to explore the potential protective mechanism of c...

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Autori principali: Hui-Ting Li, Fang Tan, Tian-Hua Zhang, Long-Hui Cao, Hong-Ying Tan, Wen-Qian Lin, Wei-An Zeng, Xin-Jin Chi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2022-05-01
Serie:BMC Pulmonary Medicine
Soggetti:
One-lung ventilation
Lung injury
Curcumin
Peroxiredoxin 6
NF-κB signaling
Accesso online:https://doi.org/10.1186/s12890-022-01988-y
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