Reactive oxygen species mediates a metabolic memory of high glucose stress signaling in bovine retinal pericytes

AIM: To investigate the role of reactive oxygen species (ROS) and antioxidant mechanism underlying the metabolic memory of bovine retinal pericytes (BRPs) induced by high glucose. METHODS: Effects of high glucose levels and culture time on BRPs viability were evaluated by CCK-8. BRPs were grown in...

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Bibliographic Details
Main Authors: Li-Wei Zhang, Han Zhao, Bai-Hua Chen
Format: Artigo
Language:Inglês
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-07-01
Series:International Journal of Ophthalmology
Subjects:
diabetic retinopathy
metabolic memory
manganese superoxide dismutase
molecular therapeutics
reactive oxygen species
Online Access:http://www.ijo.cn/en_publish/2019/7/20190703.pdf
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