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The overexpression of AUF1 in colorectal cancer predicts a poor prognosis and promotes cancer progression by activating ERK and AKT pathways

Abstract Background AUF1 is one of the AU‐rich binding proteins, which promotes rapid ARE‐mRNA degradation. Recently, it has been reported that AUF1 is involved in regulating the antioxidant system because of its capacity to bind specifically to RNA containing oxidized bases and degrade oxidized RNA...

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Главные авторы: Xin‐Yuan Tian, Jin Li, Teng‐Hui Liu, Dan‐Ni Li, Jing‐Jing Wang, He Zhang, Zhou‐Lu Deng, Fu‐Jun Chen, Jian‐Ping Cai
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley 2020-11-01
Серии:Cancer Medicine
Online-ссылка:https://doi.org/10.1002/cam4.3464
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