Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis.

The majority of nucleotide binding domain leucine rich repeats-containing (NLR) family members has yet to be functionally characterized. Of the described NLRs, most are considered to be proinflammatory and facilitate IL-1β production. However, a newly defined sub-group of NLRs that function as negat...

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Библиографические подробности
Главные авторы: Irving C Allen, Erin McElvania-TeKippe, Justin E Wilson, John D Lich, Janelle C Arthur, Jonathan T Sullivan, Miriam Braunstein, Jenny P Y Ting
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2013-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3618512?pdf=render
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