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Homozygous deletion of both GSTM1 and GSTT1 genes is associated with higher CD4+ T cell counts in Ghanaian HIV patients.

Glutathione S-transferase (GST) family of enzymes are involved in a two-stage detoxification process of a wide range of environmental toxins, carcinogens and xenobiotics. The GST enzymes play important roles in oxidative stress pathways, and polymorphisms in the GSTM1 and GSTT1 genes mediate suscept...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Joshua Agbemefa Kuleape, Emmanuel Ayitey Tagoe, Peter Puplampu, Evelyn Yayra Bonney, Osbourne Quaye
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2018-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC5967833?pdf=render
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