Engineered Schwann Cell-Based Therapies for Injury Peripheral Nerve Reconstruction

Compared with the central nervous system, the adult peripheral nervous system possesses a remarkable regenerative capacity, which is due to the strong plasticity of Schwann cells (SCs) in peripheral nerves. After peripheral nervous injury, SCs de-differentiate and transform into repair phenotypes, a...

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Autori principali: Qisong Su, Moussa Ide Nasser, Jiaming He, Gang Deng, Qing Ouyang, Donglin Zhuang, Yuzhi Deng, Haoyun Hu, Nanbo Liu, Zhetao Li, Ping Zhu, Ge Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-05-01
Serie:Frontiers in Cellular Neuroscience
Soggetti:
Schwann cells
peripheral nervous system
transcriptional regulators
tissue-engineered nerve graft
directed reprogramming
Accesso online:https://www.frontiersin.org/articles/10.3389/fncel.2022.865266/full
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