Lipidation Approaches Potentiate Adjuvant-Pulsed Immune Surveillance: A Design Rationale for Cancer Nanovaccine

Adjuvant-pulsed peptide vaccines hold great promise for the prevention and treatment of different diseases including cancer. However, it has been difficult to maximize vaccine efficacy due to numerous obstacles including the unfavorable tolerability profile of adjuvants, instability of peptide antig...

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Main Authors: Junqing Wang, Harshal Zope, Mohammad Ariful Islam, Jamie Rice, Sage Dodman, Kevin Lipert, Yunhan Chen, Bruce R. Zetter, Jinjun Shi
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Assuntos:
lipidation
nanovaccine
adjuvant
peptide antigen
Toll-like receptors
cancer
Acceso en liña:https://www.frontiersin.org/article/10.3389/fbioe.2020.00787/full
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