Lipidation Approaches Potentiate Adjuvant-Pulsed Immune Surveillance: A Design Rationale for Cancer Nanovaccine

Adjuvant-pulsed peptide vaccines hold great promise for the prevention and treatment of different diseases including cancer. However, it has been difficult to maximize vaccine efficacy due to numerous obstacles including the unfavorable tolerability profile of adjuvants, instability of peptide antig...

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Bibliographic Details
Main Authors: Junqing Wang, Harshal Zope, Mohammad Ariful Islam, Jamie Rice, Sage Dodman, Kevin Lipert, Yunhan Chen, Bruce R. Zetter, Jinjun Shi
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
lipidation
nanovaccine
adjuvant
peptide antigen
Toll-like receptors
cancer
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00787/full
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