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Increased Skeletal Muscle Fiber Cross-Sectional Area, Muscle Phenotype Shift, and Altered Insulin Signaling in Rat Hindlimb Muscles in a Prenatally Androgenized Rat Model for Polycystic Ovary Syndrome

Women with polycystic ovary syndrome (PCOS) are reported to have greater lean mass and insulin resistance. To examine muscular changes in a prenatally androgenized (PNA) rat model for PCOS, Sprague–Dawley rats were exposed to 5 mg testosterone or vehicle daily on gestational days 16–19. At 15 weeks...

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Hlavní autoři: Auryana DeChick, Rebecca Hetz, Jack Lee, Diana L. Speelman
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-10-01
Edice:International Journal of Molecular Sciences
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On-line přístup:https://www.mdpi.com/1422-0067/21/21/7918
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