Polymer Nanomedicines with Ph-Sensitive Release of Dexamethasone for the Localized Treatment of Inflammation

Polymer-drug conjugates have several advantages in controlled drug delivery to inflammation as they can accumulate and release the drug in inflamed tissues or cells, which could circumvent the shortcomings of current therapy. To improve the therapeutic potential of polymer-drug conjugates in joint i...

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Bibliographic Details
Main Authors: Alena Libánská, Eva Randárová, Franck Lager, Gilles Renault, Daniel Scherman, Tomáš Etrych
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
polymer conjugate
drug delivery
inflammation
HPMA
dexamethasone
adjuvant-induced arthritis
Online Access:https://www.mdpi.com/1999-4923/12/8/700
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