Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro

The aim of the present study was to verify the effects of fluoxetine on dysregulation of apoptosis and invasive potential in human hepatocellular carcinoma (HCC) SK-Hep1 and Hep3B cells. Cells were treated with different concentrations of fluoxetine for different times. MTT (3-(4,5-Dimethylthiazol-2...

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Autores principales: Wei-Ting Chen, Fei-Ting Hsu, Yu-Chang Liu, Cheng-Hsien Chen, Li-Cho Hsu, Song-Shei Lin
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2019-02-01
Colección:International Journal of Molecular Sciences
Materias:
fluoxetine
human hepatocellular carcinoma
NF-κB
apoptosis
Acceso en línea:https://www.mdpi.com/1422-0067/20/3/757
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