Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

Abstract Background Chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are characterized by shared exposures and clinical features, but distinct genetic and pathologic features exist. These features have not been well-studied using large-scale gene expression datase...

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Autores principales: Auyon J. Ghosh, Brian D. Hobbs, Jeong H. Yun, Aabida Saferali, Matthew Moll, Zhonghui Xu, Robert P. Chase, Jarrett Morrow, John Ziniti, Frank Sciurba, Lucas Barwick, Andrew H. Limper, Kevin Flaherty, Gerard Criner, Kevin K. Brown, Robert Wise, Fernando J. Martinez, Daniel McGoldrick, Michael H. Cho, Dawn L. DeMeo, Edwin K. Silverman, Peter J. Castaldi, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Craig P. Hersh
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2022-04-01
Colección:Respiratory Research
Materias:
COPD
IPF
RNA sequencing
Acceso en línea:https://doi.org/10.1186/s12931-022-02013-w
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