The personalized Alzheimer's disease cortical thickness index predicts likely pathology and clinical progression in mild cognitive impairment

Abstract Introduction An Alzheimer's disease (AD) biomarker adjusted for age‐related brain changes should improve specificity for AD‐related pathological burden. Methods We calculated a brain‐age‐adjusted “personalized AD cortical thickness index” (pADi) in mild cognitive impairment patients fr...

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Главные авторы: Annie M. Racine, Michael Brickhouse, David A. Wolk, Bradford C. Dickerson, Alzheimer's Disease Neuroimaging Initiative
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley 2018-01-01
Серии:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Предметы:
AD index
AD signature
Alzheimer's disease
Cortical thickness
Mild cognitive impairment
Online-ссылка:https://doi.org/10.1016/j.dadm.2018.02.007
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