The personalized Alzheimer's disease cortical thickness index predicts likely pathology and clinical progression in mild cognitive impairment

Abstract Introduction An Alzheimer's disease (AD) biomarker adjusted for age‐related brain changes should improve specificity for AD‐related pathological burden. Methods We calculated a brain‐age‐adjusted “personalized AD cortical thickness index” (pADi) in mild cognitive impairment patients fr...

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Hlavní autoři: Annie M. Racine, Michael Brickhouse, David A. Wolk, Bradford C. Dickerson, Alzheimer's Disease Neuroimaging Initiative
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2018-01-01
Edice:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Témata:
AD index
AD signature
Alzheimer's disease
Cortical thickness
Mild cognitive impairment
On-line přístup:https://doi.org/10.1016/j.dadm.2018.02.007
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