FGA Controls VEGFA Secretion to Promote Angiogenesis by Activating the VEGFR2-FAK Signalling Pathway

BackgroundOur previous work revealed the high expression of fibrinogen alpha chain (FGA) in patients with endometriosis (EM) and that it could promote the migration and invasion of endometrial stromal cells. Angiogenesis is the key condition for the development of EM. This study was aimed to elucida...

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Autors principals: Hui Li, E. Cai, Hongyan Cheng, Xue Ye, Ruiqiong Ma, Honglan Zhu, Xiaohong Chang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-04-01
Col·lecció:Frontiers in Endocrinology
Matèries:
endometriosis
fibrinogen alpha chain (FGA)
angiogenesis
VEGFA-VEFGR2 pathway
endothelial cells
Accés en línia:https://www.frontiersin.org/articles/10.3389/fendo.2022.791860/full
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