Lipocalin 2 Protects Against Escherichia coli Infection by Modulating Neutrophil and Macrophage Function

Lipocalin 2 (Lcn2) is an essential component of the antimicrobial innate immune system. It attenuates bacterial growth by binding and sequestering the iron-scavenging siderophores to prevent bacterial iron acquisition. Whereas, the ability of Lcn2 to sequester iron is well-described, the role of Lcn...

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Main Authors: Qianqian Wang, Shuhui Li, Xueyou Tang, Li Liang, Fengqin Wang, Huahua Du
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019-11-01
Sraith:Frontiers in Immunology
Ábhair:
lipocalin 2
Lcn2-deficient mice
bacterial challenge
neutrophil
macrophage
Rochtain Ar Líne:https://www.frontiersin.org/article/10.3389/fimmu.2019.02594/full
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