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Treatment of Pulpectomized Teeth With Trypsin Prior to Transplantation of Mobilized Dental Pulp Stem Cells Enhances Pulp Regeneration in Aged Dogs

There is an age-dependent decline of pulp regeneration, due to the decline of migration, proliferation, and cell survival of resident stem cells. Trypsin is a proteolytic enzyme clinically used for tissue repair. Here, we investigated the effects of trypsin pretreatment of pulpectomized teeth prior...

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Detalhes bibliográficos
Main Authors: Koichiro Iohara, Mohammed Zayed, Yoshifumi Takei, Hideto Watanabe, Misako Nakashima
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-08-01
Colecção:Frontiers in Bioengineering and Biotechnology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fbioe.2020.00983/full
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