Disrupted working memory circuitry and psychotic symptoms in 22q11.2 deletion syndrome

22q11.2 deletion syndrome (22q11DS) is a recurrent genetic mutation that is highly penetrant for psychosis. Behavioral research suggests that 22q11DS patients exhibit a characteristic neurocognitive phenotype that includes differential impairment in spatial working memory (WM). Notably, spatial WM h...

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Detalhes bibliográficos
Main Authors: C.A. Montojo, A. Ibrahim, K.H. Karlsgodt, C. Chow, A.E. Hilton, R.K. Jonas, T.K. Vesagas, C.E. Bearden
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014-01-01
Colecção:NeuroImage: Clinical
Assuntos:
Psychosis
Executive function
Velocardiofacial syndrome
Copy number variation
Endophenotype
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213158214000114
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