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Pleiotropic effects of glitazones: a double edge sword?
Glitazones (thiazolidinediones) are drugs used for diabetes mellitus type 2. By binding to Peroxisome Proliferator-Activated Receptor γ (PPARγ) they modulate transcription of genes of carbohydrate and lipid metabolism. Through PPARγ stimulation, however, glitazones also affect other genes, encompas...
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| 主要作者: | |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2011-03-01
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| 叢編: | Frontiers in Pharmacology |
| 主題: | |
| 在線閱讀: | http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00014/full |
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