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Evanescent scattering imaging of single protein binding kinetics and DNA conformation changes

Single molecule detection based on evanescent illumination usually require specially designed nanomaterials. Here, the authors show that single molecule detection can be realised on a plain glass surface via interference between the evanescent lights scattered by molecules and the natural roughness...

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Autores principales: Pengfei Zhang, Lei Zhou, Rui Wang, Xinyu Zhou, Jiapei Jiang, Zijian Wan, Shaopeng Wang
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2022-04-01
Colección:Nature Communications
Acceso en línea:https://doi.org/10.1038/s41467-022-30046-8
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